Engineering functional inorganic–organic hybrid systems: advances in siRNA therapeutics

Author:

Shen Jianliang12345ORCID,Zhang Wei12345,Qi Ruogu6789,Mao Zong-Wan12345ORCID,Shen Haifa678910

Affiliation:

1. MOE Key Laboratory of Bioinorganic and Synthetic Chemistry

2. School of Chemistry

3. Sun Yat-Sen University

4. Guangzhou 510275

5. China

6. Department of Nanomedicine

7. Houston Methodist Research Institute

8. Houston

9. USA

10. Department of Cell and Developmental Biology

Abstract

Engineering functional inorganic–organic hybrid vectors for siRNA delivery systems as a promising approach to overcome many physiological and biological obstacles, which greatly paves the way for a successful, safe and efficient platform in clinical applications.

Funder

National Natural Science Foundation of China

Ministry of Education of the People's Republic of China

Government of Guangdong Province

Wenzhou Medical University

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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