Plant-based polyphenol rich protein supplementation attenuated skeletal muscle loss and lowered the LDL level via gut microbiota remodeling in Taiwan's community-dwelling elderly

Author:

Chang Shy-Shin12,Chen Li-Han34ORCID,Huang Kuo-Chin56ORCID,Huang Shu-Wei7ORCID,Chang Chun-Chao8910,Liao Kai-Wei11,Hu En-Chi12,Chen Yu-Pin713,Chen Yi-Wen12,Hsu Po-Chi12,Huang Hui-Yu101214

Affiliation:

1. Department of Family Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

2. Department of Family Medicine, Taipei Medical University Hospital, Taipei, Taiwan

3. Institute of Fisheries Science, College of Life Science, National Taiwan University, Taipei, Taiwan

4. Department of Life Science, College of Life Science, National Taiwan University, Taipei, Taiwan

5. Department of Family Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan

6. Department of Family Medicine, National Taiwan University Hospital, Taipei, Taiwan

7. Department of Orthopedics, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan

8. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan

9. Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

10. TMU Research Center for Digestive Medicine, Taipei Medical University, Taipei 110, Taiwan

11. School of Food Safety, College of Nutrition, Taipei Medical University, Taipei, Taiwan

12. Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei, Taiwan

13. Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

14. Neuroscience Research Center, Taipei Medical University, Taipei 110, Taiwan

Abstract

A ten-week intervention with a Black Soybean Koji product improves muscle loss through the regulation of gut microbiota in elderly individuals with early sarcopenia.

Funder

National Science and Technology Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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