Embedding AIE-type Ag28Au1 nanoclusters within ZIF-8 for improved photodynamic wound healing through bacterial eradication

Author:

He Qiuxia1,Jiang Zhen1,Jiang Hongli2,Han Songjie1,Yang Guoping3ORCID,Yuan Xun1ORCID,Zhu Haiguang1ORCID

Affiliation:

1. College of Materials Science and Engineering, Qingdao University of Science and Technology (QUST), 53 Zhengzhou Rd., Shibei District, Qingdao 266042, P. R. China

2. Department of Respiratory and Critical Care Medicine, Qingdao Eighth People's Hospital, Qingdao 266121, China

3. School of Chemistry, Biology and Material Science, Jiangxi Province Key Laboratory of Synthetic Chemistry, Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang 330013, China

Abstract

A photodynamic antibacterial agent was created by encapsulating Ag28Au1 NCs in ZIF-8. This agent can eliminate 97.7% of E. coli and 91.6% of S. aureus within 5 minutes under light, promoting effective healing of bacteria-infected wounds.

Funder

National Natural Science Foundation of China

Taishan Scholar Foundation of Shandong Province

Science and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China

Publisher

Royal Society of Chemistry (RSC)

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