Peptide probes for proteases – innovations and applications for monitoring proteolytic activity

Author:

Rodriguez-Rios Maria1ORCID,Megia-Fernandez Alicia1ORCID,Norman Daniel J.2ORCID,Bradley Mark1ORCID

Affiliation:

1. EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, EH9 3FJ Edinburgh, UK

2. Technical University of Munich, Trogerstrasse, 30, 81675, Munich, Germany

Abstract

From a chemistry-based perspective, this review discusses the most recent advances in the field of substrate-based probes for the detection and analysis of proteolytic activity both in vitro and in vivo.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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