Engineered mesoporous silica-based nanoparticles as smart chemotherapy nanodevice for bortezomib administration-Reference-Cited by-同舟云学术

Engineered mesoporous silica-based nanoparticles as smart chemotherapy nanodevice for bortezomib administration

Published:2023 Issue:2 Volume:7 Page:216-229
ISSN:2052-1537
Container-title:Materials Chemistry Frontiers
language:en
Short-container-title:Mater. Chem. Front.

Author:

De Santo M.¹,Giovinazzo A.²,Fava M.¹,Mazzotta E.³,De Napoli I. E.²,Greco M.¹,Comandé A.¹,Nigro A.¹,Argurio P.²^ORCID,Perrotta I.⁴,Davoli M.⁴,Tagarelli A.⁵,Elliani R.⁵,Granato T.²,Nicolini G.³,Chiorazzi A.³,Semperboni S.³,Ballarini E.³,Crocamo C.³,Cavaletti G.³,Lombardo D.⁶,Sisci D.¹,Morelli C.¹,Leggio A.¹^ORCID,Pasqua L.²^ORCID

Affiliation:

1. Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, via P. Bucci, 87036 Arcavacata di Rende, CS, Italy

2. Department of Environmental Engineering University of Calabria, via P. Bucci, cubo 44/A, 87036, Arcavacata di Rende, CS, Italy

3. Experimental Neurology Unit, School of Medicine and Surgery and Milan Center for Neuroscience, University of Milano-Bicocca, via Cadore 48, 20900 Monza, Italy

4. Department of Biology, Ecology and Earth Sciences, Centre for Microscopy and Microanalysis (CM2), Transmission Electron Microscopy Laboratory, University of Calabria, via P. Bucci, 87036 Arcavacata di Rende, CS, Italy

5. Department of Chemistry and Chemical Technologies, University of Calabria, via P. Bucci, 87036 Arcavacata di Rende, CS, Italy

6. Institute for Chemical-Physical Processes, National Research Council, 98158 Messina, Italy

Abstract

Engineered mesoporous silica-based nanostructures for selective and pH-sensitive release of the anticancer drug bortezomib. The developed “smart chemotherapy” showed higher efficacy in vivo compared to traditional free bortezomib administration.

Funder

Horizon 2020 Framework Programme

Ministero dell'Università e della Ricerca

Regione Calabria

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QM/D2QM01009G

Reference39 articles.

1. Engineering the Interface: Nanodiamond Coating on 3D-Printed Titanium Promotes Mammalian Cell Growth and Inhibits Staphylococcus aureus Colonization