Fructose controlled ionophoric activity of a cholate–boronic acid-Reference-Cited by-同舟云学术

Fructose controlled ionophoric activity of a cholate–boronic acid

Published:2014 Issue:16 Volume:12 Page:2576-2583
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Brown James R. D.¹²³,Pintre Inmaculada C.¹²³,Webb Simon J.¹²³

Affiliation:

1. Manchester Institute of Biotechnology (MIB) and School of Chemistry

2. University of Manchester

3. Manchester M1 7DN, UK

Abstract

The transport of Na⁺ through phospholipid bilayers by Wulff-type boronic acids at pH 8.2 is reported. Concentrations of fructose greater than 5 mM strongly inhibited ionophoric activity.

Funder

Engineering and Physical Sciences Research Council

European Commission Directorate-General for Research and Innovation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00165F

Reference58 articles.

1. Boronic acid building blocks: tools for sensing and separation

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3. End-to-end conformational communication through a synthetic purinergic receptor by ligand-induced helicity switching

4. Monosaccharide-Responsive Release of Insulin from Polymersomes of Polyboroxole Block Copolymers at Neutral pH

5. Boronate-Mediated Biologic Delivery

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