pH-sensitive composite nanofibers of poly(ε-caprolactone) loaded with iron oxide nanoparticles/ammonium bicarbonate as a nanocarrier toward efficient doxorubicin release for postsurgical cancer treatment

Author:

Vo Quang Nhat Quynh1,Rezk Abdelrahman I.123ORCID,Chun Sungkun23,Park Chan Hee14,Kim Cheol Sang14

Affiliation:

1. Department of Bionanotechnology and Bioconvergence Engineering, Graduate School, Jeonbuk National University, Jeonju 561–756, Republic of Korea

2. Department of Physiology, Jeonbuk National University Medical School, Jeonju-si 54907, Republic of Korea

3. BK21FOUR 21st Century Medical Science Creative Human Resource Development Center, Republic of Korea

4. Mechanical Design Engineering, Jeonbuk National University, Jeonju 561–756, Republic of Korea

Abstract

We present pH-sensitive magnetic nanofibers for thermo-chemotherapy. This pH-sensitive approach may offer a versatile, chemo-selective method for targeted drug delivery in postsurgical breast cancer treatment.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Chemistry (miscellaneous)

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