Recent trends in the structural revision of natural products
Author:
Affiliation:
1. School of Chemistry and Biochemistry
2. Georgia Institute of Technology
3. Atlanta
4. USA
5. Aquatic Chemical Ecology Center
6. School of Biological Sciences
Abstract
Case study-based review on misassigned structures and measures to avoid erroneous assignments during structure determination.
Funder
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NP/C8NP00011E
Reference134 articles.
1. Natural Products as Sources of New Drugs from 1981 to 2014
2. Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions
3. Counting on natural products for drug design
4. Pharmacophore Reassignment for Induction of the Immunosurveillance Cytokine TRAIL
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