Copper(<scp>i</scp>)-catalyzed asymmetric [3 + 2] cycloaddition of <i>N</i>-ester acylhydrazones and β-trifluoromethyl-α,β-unsaturated ketones-Reference-Cited by-同舟云学术

Copper(i)-catalyzed asymmetric [3 + 2] cycloaddition of N-ester acylhydrazones and β-trifluoromethyl-α,β-unsaturated ketones

Published:2022 Issue:20 Volume:9 Page:5544-5550
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhu Bo¹^ORCID,Fan Huihui¹,Ding Yanan¹,Zhai Yubing¹,Wang Le¹,Wang Mengqi¹,Zhu Gongming¹,Chang Junbiao¹

Affiliation:

1. NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, 453007, P. R. China

Abstract

The first copper(i)-catalyzed asymmetric [3 + 2] cycloaddition of N-ester acylhydrazones and ketones has been developed, affording an array of chiral pyrazolidines containing a trifluoromethyl moiety bearing three vicinal stereocenters.

Funder

Central Plains Scholars and Scientists Studio Fund

National Natural Science Foundation of China

Natural Science Foundation of Henan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00993E

Reference42 articles.

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