A near-infrared and lysosome-targeted BODIPY photosensitizer for photodynamic and photothermal synergistic therapy-Reference-Cited by-同舟云学术

A near-infrared and lysosome-targeted BODIPY photosensitizer for photodynamic and photothermal synergistic therapy

Published:2023 Issue:22 Volume:21 Page:4672-4682
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liu Yan¹²³,Gao Jie¹²³,Li Hongyu¹²³^ORCID,Yang Mingyan¹²³,Lv Jiajia¹²³,Zhou Yaping¹²,Yuan Zeli¹²³,Li Xinmin¹²³^ORCID

Affiliation:

1. College of Pharmacy, Zunyi Medical University, Zunyi, Guizhou 563003, China

2. Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou 563000, China

3. Guizhou International Scientific and Technological Cooperation Base for Medical Photo-Theranostics Technology and Innovative Drug Development, Zunyi, Guizhou 563003, China

Abstract

A multifunctional BODIPY derivative Lyso-BDP was prepared. It shows near-infrared absorption and emission, photosensitizing activity, lysosomal targeting, and synergistic PDT and PTT effects, and kills cancer cells bothin vitroandin vivo.

Funder

National Natural Science Foundation of China

Guizhou Science and Technology Department

Guizhou Science and Technology Corporation Platform Talents Fund

Major Scientific and Technological Special Project of Guizhou Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00465A

Reference64 articles.