Blood–brain barrier (BBB)-on-a-chip: a promising breakthrough in brain disease research-Reference-Cited by-同舟云学术

Blood–brain barrier (BBB)-on-a-chip: a promising breakthrough in brain disease research

Published:2022 Issue:19 Volume:22 Page:3579-3602
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Peng Bo¹²^ORCID,Hao Shiping¹,Tong Ziqiu²,Bai Hua¹,Pan Sijun³,Lim Kah-Leong⁴,Li Lin¹⁵³,Voelcker Nicolas H.¹²^ORCID,Huang Wei¹⁵³

Affiliation:

1. Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, Xi'an 710072, China

2. Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia

3. The Institute of Flexible Electronics (IFE, Future Technologies), Xiamen University, Xiamen 361005, Fujian, China

4. Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, 308232, Singapore

5. Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), Nanjing 211800, China

Abstract

This review summarizes recent advances of the integration between BBB-on-a-chip (μBBB) technology and brain disease modeling. It provides a guideline to extend their applications in pathological research, drug development, and personalized medicine.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Ningbo

National Key Research and Development Program of China

Australian Research Council

Shaanxi Provincial Science and Technology Department

Northwestern Polytechnical University

Wuhan National Laboratory for Optoelectronics

Key Research and Development Projects of Shaanxi Province

Fundamental Research Funds for the Central Universities

Australian National Fabrication Facility

Publisher