Tethering-based chemogenetic approaches for the modulation of protein function in live cells
Author:
Affiliation:
1. Institute of Molecular Physiology
2. Shenzhen Bay Laboratory
3. Shenzhen 518132
4. China
5. School of Chemistry
6. Department of Biomolecular Engineering
7. Graduate School of Engineering
8. Nagoya University
9. Nagoya 464-8603
10. Japan
Abstract
Approaches for selective and rapid modulation are ideal for investigating the physiological roles of proteins. This review focuses on chemogenetic approaches in which designer molecules are attached to the target protein for the modulation of proteins in live cells.
Funder
Royal Society
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/CS/D1CS00059D
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