A thermo-/pH-responsive hydrogel (PNIPAM-PDMA-PAA) with diverse nanostructures and gel behaviors as a general drug carrier for drug release

Author:

Chen Yan12345,Gao Yuting12345,da Silva Lucília P.678910,Pirraco Rogério P.678910,Ma Mengdi12345,Yang Liming12345,Reis Rui L.678910ORCID,Chen Jie12345ORCID

Affiliation:

1. Department of Chemical Engineering and technology

2. School of Environmental and Chemical Engineering

3. Shanghai University

4. Shanghai 200444

5. P. R. China

6. 3B's Research Group - Biomaterials

7. Biodegradables and Biomimetics

8. University of Minho

9. Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine

10. 4805-017 Barco, Guimarães

Abstract

The aim of this research was to develop thermo- and pH-responsive hydrogels based on H-bonds for the sustained release of the small-molecule model drug Methylene Blue (MB).

Funder

Shanghai University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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