Chirality in metal-based anticancer agents
Author:
Affiliation:
1. College of Chemistry and Environmental Engineering
2. Shenzhen University
3. Shenzhen
4. 518060
5. P. R. China
6. Department of Chemistry
7. University of Warwick
8. Coventry
9. UK
Abstract
Chiral metal-based drugs are currently an interesting and rapidly growing field in anticancer research. Here the different chiral metal-based anticancer agents and the extent to which the chiral resolution affects their biological properties are discussed. This review will aid the design of new potent and efficient chiral metal-based anticancer drugs that exploit the unique properties combined with their potential selectivity toward targeted chiral biomolecules.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Link
http://pubs.rsc.org/en/content/articlepdf/2018/DT/C8DT00089A
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