Synthesis of small protein domains by automated flow chemistry

Author:

Ferentzi Kristóf12ORCID,Nagy-Fazekas Dóra12,Farkas Viktor23ORCID,Perczel András23ORCID

Affiliation:

1. Hevesy György PhD School of Chemistry, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány. 1/A, Budapest, H-1117, Hungary

2. Laboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány. 1/A, Budapest, H-1117, Hungary

3. HUN-REN-ELTE Protein Modeling Research Group, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány. 1/A, Budapest, H-1117, Hungary

Abstract

The smart peptide chemistry in flow method, or SPF for short, has been fine-tuned to enable the efficient, rapid, cost-effective and more environmentally friendly synthesis of small domain proteins, each representing a basic fold type.

Funder

Innovációs és Technológiai Minisztérium

Nemzeti Kutatási, Fejlesztési és Innovaciós Alap

European Commission

Institut de Recherches Servier

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

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