Synthesis of 6′-galactosyllactose, a deviant human milk oligosaccharide, with the aid of <i>Candida antarctica</i> lipase-B-Reference-Cited by-同舟云学术

Synthesis of 6′-galactosyllactose, a deviant human milk oligosaccharide, with the aid of Candida antarctica lipase-B

Published:2022 Issue:23 Volume:20 Page:4724-4735
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hunt Kaarel Erik¹²,García-Sosa Alfonso T.³,Shalima Tatsiana¹^ORCID,Maran Uko³,Vilu Raivo²,Kanger Tõnis¹^ORCID

Affiliation:

1. Department of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618 Tallinn, Estonia

2. Centre of Food and Fermentation Technologies, Akadeemia tee 15A, 12618 Tallinn, Estonia

3. Department of Chemistry, University of Tartu, Ravila Street 14a, 50411 Tartu, Estonia

Abstract

Using Novozyme N435 in organic media led to selective deacetylation of various pyranose saccharides. Two of the products were then used to synthesise 6'-galactosyllactose in overall a short pathway.

Funder

European Regional Development Fund

Haridus- ja Teadusministeerium

Eesti Teaduste Akadeemia

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00550F

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