Chemical probes of Skp2-mediated p27 ubiquitylation and degradation-Reference-Cited by-同舟云学术

Chemical probes of Skp2-mediated p27 ubiquitylation and degradation

Author:

Lough Lea¹²³⁴^ORCID,Sherman Dan¹²³⁴^ORCID,Ni Eric¹²³⁴^ORCID,Young Lauren M.¹²³⁴^ORCID,Hao Bing⁵⁶⁷⁴^ORCID,Cardozo Timothy¹²³⁴^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Pharmacology

2. New York University School of Medicine

3. New York

4. USA

5. Department of Molecular Biology and Biophysics

6. University of Connecticut Health Center

7. Farmington

Abstract

A meta-analysis of Skp2 inhibitors based on bioactivity, structure, and medicinal chemistry was used to identify validated Skp2 pharmaceutical hits.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

Reference41 articles.

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