Synthesis and cytotoxicity studies of Cu(i) and Ag(i) complexes based on sterically hindered β-diketonates with different degrees of fluorination

Author:

Pellei Maura1ORCID,Del Gobbo Jo’1,Caviglia Miriam1,Karade Deepika V.2,Gandin Valentina3,Marzano Cristina3,Noonikara Poyil Anurag2ORCID,Dias H. V. Rasika2ORCID,Santini Carlo1ORCID

Affiliation:

1. School of Science and Technology, Chemistry Division, University of Camerino, Via Madonna delle Carceri (ChIP), 62032 Camerino, Macerata, Italy

2. Department of Chemistry and Biochemistry, The University of Texas at Arlington, Box 19065, Arlington, Texas 76019-0065, USA

3. Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131 Padova, Italy

Abstract

New Cu(i) and Ag(i) phosphane complexes supported by β-diketonate ligands were synthesized and evaluated for their antitumor activity by 2D and 3D cell viability studies.

Funder

Ministero dell'Università e della Ricerca

Università degli Studi di Camerino

Università degli Studi di Padova

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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