Polymeric assembly of hyperbranched building blocks to establish tunable nanoplatforms for lysosome acidity-responsive gene/drug co-delivery

Author:

Jia Hui-Zhen1234,Zhang Wei56728,Wang Xu-Li9101112,Yang Bin1234,Chen Wei-Hai1234,Chen Si1234,Chen Gang56728,Zhao Yi-Fang56728,Zhuo Ren-Xi1234,Feng Jun1234,Zhang Xian-Zheng1234

Affiliation:

1. Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry

2. Wuhan University

3. Wuhan 430072

4. China

5. The State Key Laboratory Breeding Base of Basic Science of Stomatology & Key Laboratory of Oral Biomedicine Ministry of Education

6. and Department of Oral and Maxillofacial Surgery

7. School & Hospital of Stomatology

8. Wuhan

9. Department of Pharmaceutics and Pharmaceutical Chemistry

10. University of Utah

11. Salt Lake City

12. USA

Abstract

A pH-reversible polymeric assembly approach was developed to build tunable nanoplatforms, based on the boronate-linked assembly between hyperbranched building blocks.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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