Synthesis and biological evaluation of ruthenium polypyridine complexes with 18β-glycyrrhetinic acid as antibacterial agents against Staphylococcus aureus-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of ruthenium polypyridine complexes with 18β-glycyrrhetinic acid as antibacterial agents against Staphylococcus aureus

Published:2022 Issue:3 Volume:51 Page:1099-1111
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Zhang Qin¹,Xiong Yanshi¹^ORCID,Cheng Jianxin¹,Tan Yanhui²,Liao Xiangwen¹^ORCID,Wang Jintao¹^ORCID

Affiliation:

1. Jiangxi Provincial Key Laboratory of Drug Design and Evaluation, School of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang, 330013, People's Republic of China

2. State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, People's Republic of China

Abstract

Four new Ru(ii) complexes with GA derivatives were synthesized and characterized. These complexes showed significant antibacterial ability against S. aureus both in vitro and in vivo.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Jiangxi Science and Technology Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/DT/D1DT02692E

Reference42 articles.

1. Resistance or decreased susceptibility to glycopeptides, daptomycin, and linezolid in methicillin-resistant Staphylococcus aureus