Efficient delivery of chlorin e6 into ovarian cancer cells with octalysine conjugated superparamagnetic iron oxide nanoparticles for effective photodynamic therapy-Reference-Cited by-同舟云学术

Efficient delivery of chlorin e6 into ovarian cancer cells with octalysine conjugated superparamagnetic iron oxide nanoparticles for effective photodynamic therapy

Published:2016 Issue:47 Volume:4 Page:7741-7748
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhao Li¹²³⁴⁵,Yang Hongkuan⁶⁷⁸⁹¹⁰,Amano Tsukuru¹¹⁷⁸⁹¹⁰,Qin Hongmei⁵¹²¹³¹⁰,Zheng Luyi¹¹⁷⁸⁹¹⁰,Takahashi Akimasa¹¹⁷⁸⁹¹⁰,Zhao Shiguang¹⁴¹⁵¹⁶¹⁷⁴,Tooyama Ikuo⁶⁷⁸⁹¹⁰,Murakami Takashi¹¹⁷⁸⁹¹⁰,Komatsu Naoki⁵¹²¹³¹⁰

Affiliation:

1. School of Radiation Medicine and Protection and Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions

2. Soochow University

3. Suzhou

4. China

5. Graduate School of Human and Environmental Studies

6. Molecular Neuroscience Research Center

7. Shiga University of Medical Science

8. Seta Tsukinowa-cho

9. Otsu

10. Japan

11. Department of Obstetrics and Gynecology

12. Kyoto University

13. Sakyo-ku

14. Department of Neurosurgery

15. 1st Affiliated Hospital

16. Harbin Medical University

17. Harbin 150001

Abstract

Chlorin e6, loaded on the surface of SPION-PG-Lys₈ through electrostatic attraction, was delivered preferentially into mitochondria of SKOV3 ovarian cancer cells, improving efficacy of photodynamic therapy significantly.

Funder

Naito Foundation

National Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2016/TB/C6TB01988A

Reference35 articles.

1. Photodynamic therapy for cancer

2. Folic acid conjugated ferritins as photosensitizer carriers for photodynamic therapy