Cytotoxic triterpenoids fromAntrodia camphorataas sensitizers of paclitaxel

Author:

Li Bin12345ORCID,Kuang Yi12345,Zhang Meng12345,He Jun-Bin12345,Xu Lu-Lu12345,Leung Chung-Hang67895ORCID,Ma Dik-Lung1011125ORCID,Lo Jen-Yu13141516,Qiao Xue12345ORCID,Ye Min12345ORCID

Affiliation:

1. State Key Laboratory of Natural and Biomimetic Drugs & Key Laboratory of Molecular Cardiovascular Sciences of Ministry of Education

2. School of Pharmaceutical Sciences

3. Peking University

4. Beijing 100191

5. People's Republic of China

6. State Key Laboratory of Quality Research in Chinese Medicine

7. Institute of Chinese Medical Sciences

8. University of Macau

9. Macau

10. Department of Chemistry

11. Hong Kong Baptist University

12. Hong Kong

13. Honest & Humble Biotechnology Co.

14. Ltd.

15. New Taipei City 251

16. Taiwan

Abstract

In an attempt to discover anticancer triterpenoids from the medicinal fungusAntrodia camphorata, a total of 60 triterpenoids (1–60) including 18 new ones (antcamphins M–X,1–18) were isolated from its dish cultures.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference22 articles.

1. Chang Gung Memorial Hospital , 2011 , https://clinicaltrials.gov/ct2/show/NCT01287286

2. Antrodia cinnamomeaalleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice

3. Efficacy of Antioxidants as a Complementary and Alternative Medicine (CAM) in Combination With the Chemotherapeutic Agent Doxorubicin

4. Taiwan Formosa Cancer Foundation , The results of nutritional cognition of cancer patients , 2005 , Internet at http://www.canceraway.org.tw/uploads/200509.pdf , Accessed 28 Feb 2014

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