Open questions on toxic heavy metals Cd, Hg and Pb binding small components of DNA and nucleobases. Are there any predictable trends?

Author:

Pérez-Barcia Álvaro1ORCID,Montero-Campillo M. Merced2ORCID,Lamsabhi Al Mokhtar2ORCID,Salpin Jean-Yves34ORCID,Yáñez Manuel2ORCID

Affiliation:

1. Departamento de Química Física, Universidad de Vigo, Lagoas-Marcosende s/n, 36310 Vigo, Spain

2. Departamento de Química, Módulo 13, Facultad de Ciencias, and Institute of Advanced Chemical Sciences (IAdChem), Universidad Autónoma de Madrid, Campus de Excelencia UAM-CSIC, Cantoblanco, 28049 Madrid, Spain

3. Université Paris-Saclay, Univ. Evry, CNRS, LAMBE, 91025, Evry-Courcouronnes, France

4. LAMBE, CY Cergy Paris Université, CNRS, 95000 Cergy, France

Abstract

This article presents a bibliographic compilation of experimental and theoretical work on Cd, Hg, and Pb, and analyzes in detail the bonding of M2+ and CH3M+ (M = Zn, Cd, Hg, Pb) with urea and thiourea as suitable models for larger biochemical bases.

Funder

Ministerio de Ciencia, Innovación y Universidades

Comunidad de Madrid

Universidade de Vigo

Universidad Autónoma de Madrid

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

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