Challenges in natural product-based drug discovery assisted with<i>in silico</i>-based methods-Reference-Cited by-同舟云学术

Challenges in natural product-based drug discovery assisted within silico-based methods

Published:2023 Issue:45 Volume:13 Page:31578-31594
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Simoben Conrad V.¹²³^ORCID,Babiaka Smith B.¹⁴⁵^ORCID,Moumbock Aurélien F. A.⁶^ORCID,Namba-Nzanguim Cyril T.¹⁴^ORCID,Eni Donatus Bekindaka¹⁴^ORCID,Medina-Franco José L.⁷^ORCID,Günther Stefan⁶^ORCID,Ntie-Kang Fidele¹⁴⁸^ORCID,Sippl Wolfgang⁸^ORCID

Affiliation:

1. Center for Drug Discovery, Faculty of Science, University of Buea, P.O. Box 63, Buea CM-00237, Cameroon

2. Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada

3. Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada

4. Department of Chemistry, University of Buea, Buea, Cameroon

5. Department of Microbial Bioactive Compounds, Interfaculty Institute for Microbiology and Infection Medicine, University of Tübingen, 72076 Tübingen, Germany

6. Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany

7. DIFACQUIM Research Group, Department of Pharmacy, School of Chemistry, Universidad Nacional Autónoma de México, Avenida Universidad 3000, Mexico City 04510, Mexico

8. Institute of Pharmacy, Martin-Luther University Halle-Wittenberg, Halle (Saale), Germany

Abstract

This review uses documented studies to highlight current difficulties faced by natural product drug discovery scientists usingin silicomethods. This will provide interested scientists in this field of research an idea of what they can expect.

Funder

Alexander von Humboldt-Stiftung

Bill and Melinda Gates Foundation

LifeArc

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA06831E

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