In vivo imaging of hepatocellular nitric oxide using a hepatocyte-targeting fluorescent sensor

Author:

Zhang Peisheng12345ORCID,Tian Yong12345,Liu Hui12345,Ren Junyu12345,Wang Hong12345,Zeng Rongjin12345,Long Yunfei12345ORCID,Chen Jian12345ORCID

Affiliation:

1. Key Laboratory of Theoretical Organic Chemistry and Functional Molecule of Ministry of Education

2. Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine Polymers

3. Hunan Province College Key Laboratory of QSAR/QSPR

4. School of Chemistry and Chemical Engineering

5. Hunan University of Science and Technology

Abstract

A hepatocyte-targeting fluorescent NO sensor has been fabricated with good water solubility, excellent selectivity, and high sensitivity (∼1.62 nM).

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hunan Province

South China University of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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