Inflammatory activation of human serum albumin- or ovalbumin-modified chitosan particles to macrophages and their immune response in human whole blood

Author:

Zhang Yixian1234,Du Wang1234,Smuda Kathrin5678,Georgieva Radostina5678,Bäumler Hans5678,Gao Changyou12349ORCID

Affiliation:

1. MOE Key Laboratory of Macromolecular Synthesis and Functionalization

2. Department of Polymer Science and Engineering, Zhejiang University

3. Hangzhou 310027

4. China

5. Institute of Transfusion Medicine and Berlin-Brandenburg Center for Regenerative Therapies

6. Charité-Universitätsmedizin Berlin

7. 10117 Berlin

8. Germany

9. Dr Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine

Abstract

Chitosan particles modified with different albumins cause immune response in human whole blood via platelet activation and phagocytosis.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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