ICAM-1 targeted and ROS-responsive nanoparticles for the treatment of acute lung injury

Author:

Ran Yu1,Yin Shanmei1,Xie Pei12,Liu Yaxue1,Wang Ying13,Yin Zongning1ORCID

Affiliation:

1. Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China

2. Co-Construction Collaborative Innovation Center for Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, Shaanxi University of Chinese Medicine, Xianyang 712038, China

3. School of Pharmacy, Chengdu University, Chengdu, 610106, China

Abstract

A schematic diagram of Dex/PSB-γ3 NPs targeting high ICAM-1-expressing cells and their depolymerization under ROS stimulation for the treatment of ALI.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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