Effects of pectin's degree of methyl esterification on TLR2-mediated IL-8 secretion and tight junction gene expression in intestinal epithelial cells: influence of soluble TLR2-Reference-Cited by-同舟云学术

Effects of pectin's degree of methyl esterification on TLR2-mediated IL-8 secretion and tight junction gene expression in intestinal epithelial cells: influence of soluble TLR2

Published:2024 Issue:2 Volume:15 Page:569-579
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Gasaly Naschla¹²^ORCID,Tang Xin¹^ORCID,Chen Xiaochen¹,Bellalta Sofía¹,Hermoso Marcela A.²³,de Vos Paul¹

Affiliation:

1. Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University of Groningen and University Medical Center Groningen, Hanzeplein 1, EA 11, 9713 GZ, Groningen, The Netherlands

2. Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands

3. Laboratory of Innate Immunity, Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile

Abstract

Low DM-pectins have strong anti-inflammatory effects and prevents dysregulation of TJ-related genes. The effects of pectin are dependent on DM of the pectin, the magnitude of TLR2 expression and on circulating sTLR2 in blood.

Funder

Universidad de Chile

Rijksuniversiteit Groningen

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D3FO03673A

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