Mixed polymer and bioconjugate core/shell electrospun fibres for biphasic protein release

Author:

Adala Inchirah1234,Ramis Jopeth1234,Ntone Moussinga Cynthia1234,Janowski Isabella1234,Amer Mahetab H.5674ORCID,Bennett Andrew J.84,Alexander Cameron1234ORCID,Rose Felicity R. A. J.1234ORCID

Affiliation:

1. School of Pharmacy

2. University of Nottingham

3. Nottingham

4. UK

5. School of Molecular and Cellular Biology

6. University of Leeds

7. Leeds

8. School of Life Sciences, University of Nottingham

Abstract

We report the fabrication of a coaxial electrospun scaffold with a bioactive molecule in the core and a protein conjugated at the surface. To construct the scaffold, we chose polyethylene oxide for the core material and a polycaprolactone/Jeffamine blend for the shell.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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