Discovery of novel cinnamylidene-thiazolidinedione derivatives as PTP-1B inhibitors for the management of type 2 diabetes
Author:
Affiliation:
1. School of Pharmaceutical Sciences
2. Guru Ghasidas Central University
3. Bilaspur-495 009
4. India
5. University Institute of Pharmaceutical Sciences
6. Panjab University
Abstract
Synthesis, biological evaluation,in silicobinding affinity prediction and 3D-QSAR studies of cinnamylidene-thiazolidinedione derivatives was performed as inhibitors of PTP-1B.
Funder
University Grants Commission
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA24501C
Reference62 articles.
1. Design of Novel Biphenyl-2-thioxothiazolidin-4-one Derivatives as Potential Protein Tyrosine Phosphatase (PTP)-1B Inhibitors Using Molecular Docking Study
2. Protein Tyrosine Phosphatase 1B Inhibitors: A Molecular Level Legitimate Approach for the Management of Diabetes Mellitus
3. Diagnosis and Classification of Diabetes Mellitus, http://www.care.diabetesjournals.org/content/diacare/32/Supplement_1/S62.full.pdf, accessed October 2015
4. Molecular docking assisted 3D-QSAR study of benzylidene-2,4-thiazolidinedione derivatives as PTP-1B inhibitors for the management of Type-2 diabetes mellitus
5. Recent Studies of Aldose Reductase Enzyme Inhibition for Diabetic Complications
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