A multivariate metal–organic framework based pH-responsive dual-drug delivery system for chemotherapy and chemodynamic therapy

Author:

Akbar Muhammad Usman12ORCID,Akbar Arslan2,Saddozai Umair Ali Khan3,Khan Malik Ihsan Ullah4,Zaheer Muhammad2ORCID,Badar Muhammad1

Affiliation:

1. Gomal Center of Biochemistry and Biotechnology, Gomal University, Dera Ismail Khan, 29050, Pakistan

2. Department of Chemistry and Chemical Engineering, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences (LUMS), Lahore, 54792, Pakistan

3. Department of Preventive Medicine, Institute of Biomedical Informatics, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China

4. Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, 54000, Pakistan

Abstract

By combining two different ligands and metals, MOFs can be fine-tuned for effective encapsulation and delivery of two anticancer drugs.

Funder

Lahore University of Management Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Chemistry (miscellaneous)

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