Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability-Reference-Cited by-同舟云学术

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Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability

Published:2020 Issue:21 Volume:11 Page:5577-5591
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kannan Srinivasaraghavan¹²³⁴^ORCID,Aronica Pietro G. A.¹²³⁴,Ng Simon⁵²⁶,Gek Lian Dawn Thean⁵²⁶,Frosi Yuri⁵²⁶,Chee Sharon⁵²⁶,Shimin Jiang⁵²⁶,Yuen Tsz Ying⁷²⁸^ORCID,Sadruddin Ahmad⁹¹⁰⁴⁴,Kaan Hung Yi Kristal⁹¹⁰⁴⁴,Chandramohan Arun⁹¹⁰⁴⁴,Wong Jin Huei¹²³⁴,Tan Yaw Sing¹²³⁴,Chang Zi Wei¹¹²⁶^ORCID,Ferrer-Gago Fernando J.⁵²⁶,Arumugam Prakash¹²³⁴,Han Yi¹²¹³¹⁴,Chen Shiying¹²¹³¹⁴,Rénia Laurent¹¹²⁶,Brown Christopher J.⁵²⁶,Johannes Charles W.⁷²⁸,Henry Brian⁹¹⁰⁴⁴,Lane David P.⁵²⁶,Sawyer Tomi K.¹²¹⁵¹⁴,Verma Chandra S.¹²³⁴¹⁶^ORCID,Partridge Anthony W.⁹¹⁰⁴⁴^ORCID

Affiliation:

1. Bioinformatics Institute

2. Agency for Science, Technology and Research (A*STAR)

3. Singapore 138671

4. Singapore

5. p53 Laboratory

6. Singapore 138648

7. Institute of Chemical & Engineering Science

8. Singapore 138665

9. MSD International

10. Translation Medicine Research Centre

11. Singapore Immunology Network (SIgN)

12. Merck & Co., Inc.

13. Kenilworth

14. USA

15. Boston

16. School of Biological Sciences

Abstract

Peptide-based molecules hold great potential as targeted inhibitors of intracellular protein–protein interactions (PPIs).

Funder

Agency for Science, Technology and Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/C9SC06383H

Reference68 articles.

1. Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics

2. Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery

3. Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

4. Modulating protein–protein interactions: the potential of peptides

5. Therapeutic peptides: Historical perspectives, current development trends, and future directions

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