Total synthesis and biological activity of dolastatin 16-Reference-Cited by-同舟云学术

Total synthesis and biological activity of dolastatin 16

Published:2017 Issue:5 Volume:15 Page:1140-1150
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Casalme Loida O.¹²³⁴,Yamauchi Arisa¹²³⁴,Sato Akinori¹²³⁴,Petitbois Julie G.¹²³⁴,Nogata Yasuyuki⁵⁶⁷⁴,Yoshimura Erina⁸⁹¹⁰⁴,Okino Tatsufumi¹²³⁴^ORCID,Umezawa Taiki¹²³⁴^ORCID,Matsuda Fuyuhiko¹²³⁴

Affiliation:

1. Graduate School of Environmental Science

2. Hokkaido University

3. N10W5 Sapporo 060-0810

4. Japan

5. Environmental Science Research Laboratory

6. Central Research Institute of Electric Power Industry

7. Chiba 270-1194

8. CERES

9. Inc.

10. Chiba 270-1153

Abstract

The total synthesis of dolastatin 16, a macrocyclic depsipeptide first isolated from the sea hareDolabella auriculariaas a potential antineoplastic metabolite by Pettitet al., was achieved in a convergent manner.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C6OB02657E

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