Efficiently normalizing leukopoiesis by gadofullerene nanoparticles to ameliorate radiation-triggered myelosuppression

Author:

Jia Wang12,Li Xue12,Zhang Tian3,Wang Chunru12ORCID,Zhen Mingming12ORCID

Affiliation:

1. Beijing National Laboratory for Molecular Sciences, Key Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China

2. University of Chinese Academy of Sciences, Beijing 100049, China

3. Beijing ChaoYang Hospital, Beijing 100020, China

Abstract

GFNPs enhance the leukopoiesis through affecting the differentiation, development, and maturation of leukocytes (e.g., NEUT and B cells), which leads to the remission of myelosuppression and the increase of leukocytes after radiotherapy.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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