Synthesis and characterization of 18F-labeled hydrazinocurcumin derivatives for tumor imaging
Author:
Affiliation:
1. Department of Nuclear Medicine
2. Samsung Medical Center
3. Sungkyunkwan University School of Medicine
4. Seoul 06351
5. Korea
Abstract
Radiolabeled hydrazinocurcumin derivatives, [18F]1 and [18F]2 were synthesized and both radioligands were resistant to reductive metabolism. MicroPET images of C6 glioma xenografted mice showed high tumor uptake and retention of [18F]2.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA15380H
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