Bioinspired nonheme iron complex that triggers mitochondrial apoptotic signalling pathway specifically for colorectal cancer cells-Reference-Cited by-同舟云学术

Bioinspired nonheme iron complex that triggers mitochondrial apoptotic signalling pathway specifically for colorectal cancer cells

Published:2022 Issue:3 Volume:13 Page:737-747
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Lee Yool¹,Oh Chaeun²^ORCID,Kim Jin³^ORCID,Park Myong-Suk⁴,Bae Woo Kyun⁴⁵,Yoo Kyung Hyun²,Hong Seungwoo¹^ORCID

Affiliation:

1. Department of Chemistry, Sookmyung Women's University, Seoul 04310, Korea

2. Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea

3. Department of Chemistry, Sunchon National University, Suncheon 57922, Korea

4. Division of Hemato-Oncology, Department of Internal Medicine, Chonnam National University Medical School and Hwasun Hospital, Hwasun, Republic of Korea

5. Combinatorial Tumor Immunotherapy MRC Center, Chonnam National University Medical School, Hwasun, Republic of Korea

Abstract

A water-soluble iron complex that produces hydroxyl radical species triggers colorectal cancer cell death via the mitochondrial apoptotic pathway.

Funder

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D1SC05094J

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