Fabrication of AS1411 aptamer functionalized Gd2O3-based molecular magnetic resonance imaging (mMRI) nanoprobe for renal carcinoma cell imaging
Author:
Affiliation:
1. Department of Radiology
2. Affiliated Hospital of Xuzhou Medical College
3. Xuzhou 221006
4. China
5. School of Medical Imaging
6. Xuzhou Medical College
7. Xuzhou 221004
Abstract
A molecular MRI nanoprobe for the sensitive and specific MRI of renal carcinoma cells with BSA-Gd2O3nanoparticles as MRI contrast agents, mesoporous silica nanoparticles as nanocarriers and AS1411 aptamer as targeting molecule was developed.
Funder
Natural Science Foundation of Jiangsu Province
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA17211J
Reference29 articles.
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