Hydroxytyrosol alleviates oxidative stress and neuroinflammation and enhances hippocampal neurotrophic signaling to improve stress-induced depressive behaviors in mice-Reference-Cited by-同舟云学术

Hydroxytyrosol alleviates oxidative stress and neuroinflammation and enhances hippocampal neurotrophic signaling to improve stress-induced depressive behaviors in mice

Published:2021 Issue:12 Volume:12 Page:5478-5487
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhao Yun-Tao¹²³⁴⁵^ORCID,Zhang Lulu¹²³⁴^ORCID,Yin Haowen¹²³⁴,Shen Ling⁶²³⁴,Zheng Wenjing¹²³⁴,Zhang Kun¹²³⁴,Zeng Jian¹²³⁴,Hu Chuanyin⁷⁸³⁴^ORCID,Liu You¹²³⁴^ORCID

Affiliation:

1. College of Food Science and Technology

2. Guangdong Ocean University

3. Zhanjiang

4. P.R. China

5. Shenzhen Research Institute

6. College of Agriculture

7. Department of Biology

8. Guangdong Medical University

Abstract

Hydroxytyrosol exerts antidepressant-like effects in mice by reducing oxidative stress, suppressing neuroinflammation, and enhancing the function of neurotrophic factors.

Funder

Natural Science Foundation of Guangdong Province

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO00210D

Reference46 articles.

1. NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation

2. Depression