TEMPO/PhI(OAc)<sub>2</sub> promotes the α-aminophosphinoylation of alcohols with amines and H-phosphine oxides in aqueous medium-Reference-Cited by-同舟云学术

TEMPO/PhI(OAc)₂ promotes the α-aminophosphinoylation of alcohols with amines and H-phosphine oxides in aqueous medium

Published:2024 Issue:19 Volume:22 Page:3860-3865
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Huang Qiang¹^ORCID,Jin Xin¹,Wu Lvjia¹,Li Jiangdong²,Xing Qianlu³,Wang Xianheng¹,Zhao Changkuo¹^ORCID

Affiliation:

1. School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou 563000, P. R. China

2. School of Public Health, Zunyi Medical University, Zunyi, Guizhou 563000, P. R. China

3. Department of Pediatric, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563000, P. R. China

Abstract

The aminophosphinoylation of alcohols with amines and H-phosphine oxides provides an efficient and mild approach to access various α-aminoalkylphosphine oxides in good yields with good tolerance of functional groups using H2O as a clean solvent.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guizhou Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00302K

Reference74 articles.

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