Mitochondria-targeted half-sandwich rutheniumII diimine complexes: anticancer and antimetastasis via ROS-mediated signalling-Reference-Cited by-同舟云学术

Mitochondria-targeted half-sandwich rutheniumII diimine complexes: anticancer and antimetastasis via ROS-mediated signalling

Published:2018 Issue:9 Volume:5 Page:2100-2105
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Xu Zhishan¹²³⁴⁵,Kong Deliang⁶⁷⁸⁹¹⁰,He Xiangdong⁶⁷⁸⁹¹⁰,Guo Lihua⁶⁷⁸⁹¹⁰^ORCID,Ge Xingxing⁶⁷⁸⁹¹⁰,Liu Xicheng⁶⁷⁸⁹¹⁰,Zhang Hairong⁶⁷⁸⁹¹⁰,Li Juanjuan⁶⁷⁸⁹¹⁰,Yang Yuliang⁶⁷⁸⁹¹⁰,Liu Zhe⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. College of Chemistry

2. Chemical Engineering and Materials Science

3. Shandong Normal University

4. Jinan 250014

5. China

6. The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical

7. Intermediates and Analysis of Natural Medicine

8. Department of Chemistry and Chemical Engineering

9. Qufu Normal University

10. Qufu 273165

Abstract

Two half-sandwich Ru^II diimine complexes combine features of bioimaging, anticancer and antimetastasis properties into one molecule. The complexes target mitochondria and damage mitochondrial integrity.

Funder

National Natural Science Foundation of China

Taishan Scholar Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QI/C8QI00476E

Reference41 articles.

1. A systematic analysis of FDA-approved anticancer drugs

2. The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials