Multifunctional calcium polyphenol networks reverse the hostile microenvironment of trauma for preventing postoperative peritoneal adhesions

Author:

Zhang Pei1,Gong Yan2,Pan Qingqing1,Fan Zhenlin1,Li Genke13,Pei Mengyu1,Zhang Junhe1,Wang Tianyun14,Zhou Guangdong12,Wang Xiansong12ORCID,Ren Wenjie13

Affiliation:

1. The Third Affiliated Hospital of Xinxiang Medical University, Institutes of Health Central Plain, Clinical Medical Center of Tissue Engineering and Regeneration, Xinxiang Medical University, Xinxiang, China

2. Shanghai Key Laboratory of Tissue Engineering, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China

3. Department of Orthopedics, the First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan Province, China

4. Xinxiang University, Xinxiang, Henan Province 453000, China

Abstract

CaPNs are synthesized in one step from Ca2+ and gallic acid and prolonged Ca2+ and gallic acid release which prevent postoperative adhesions during the hostile microenvironment of trauma via exerting their multiple functions.

Funder

Xinxiang Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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