Unusual immunosuppressive pyridine-containing bisnor- (c23), tetranor- (c21) and pentanor- (c20) sesterterpenoids from Tibetan Leucosceptrum canum-Reference-Cited by-同舟云学术

Unusual immunosuppressive pyridine-containing bisnor- (c₂₃), tetranor- (c₂₁) and pentanor- (c₂₀) sesterterpenoids from Tibetan Leucosceptrum canum

Published:2024 Issue:15 Volume:22 Page:3019-3024
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Li Man¹²,Feng Ling¹³,Zhang Han¹²,Liu Yan-Chun¹²,Zhou Ting-Ting¹²,Zheng Yu¹,Guo Kai⁴,Liu Yan⁴,Li Sheng-Hong¹⁴^ORCID

Affiliation:

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China

2. University of Chinese Academy of Sciences, Beijing 100049, P. R. China

3. School of Forestry, Southwest Forestry University, Kunming 650224, P. R. China

4. State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China

Abstract

Six unusual pyridine-containing bisnor- (C23), tetranor- (C21) and pentanor- (C20) sesterterpenoids were obtained from the medicinal plant Leucosceptrum canum of Tibetan origin. The immunosuppressive activities of these sesterterpenoids were observed.

Funder

National Natural Science Foundation of China

Applied Basic Research Foundation of Yunnan Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00334A

Reference10 articles.

1. The untapped potential of plant sesterterpenoids: chemistry, biological activities and biosynthesis

2. Glandular Trichomes of Leucosceptrum canum Harbor Defensive Sesterterpenoids

3. Gentianelloids A and B: Immunosuppressive 10,11-seco-Gentianellane Sesterterpenoids from the Traditional Uighur Medicine Gentianella turkestanorum

4. Immunosuppressive and Adipogenesis Inhibitory Sesterterpenoids with a Macrocyclic Ether System from Eurysolen gracilis

5. Leucosceptrane Sesterterpenoids as a New Type of Natural Immunosuppressive Agents in Treating Sepsis

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