Light-inducible nanodrug-mediated photodynamic and anti-apoptotic synergy for enhanced immunotherapy in triple-negative breast cancer-Reference-Cited by-同舟云学术

Light-inducible nanodrug-mediated photodynamic and anti-apoptotic synergy for enhanced immunotherapy in triple-negative breast cancer

Published:2024 Issue:10 Volume:12 Page:2639-2647
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Huang Jing¹²³,Liu Xingliang¹²³,Lin Minzhao²,Xiao Zecong¹^ORCID,Shuai Xintao¹²^ORCID

Affiliation:

1. Nanomedicine Research Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, P. R. China

2. PCFM Lab of Ministry of Education, School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou 510275, P. R. China

3. School of Engineering, Westlake University, Hangzhou 310030, P. R. China

Abstract

An ROS-labile nanodrug co-encapsulating Ce6 and a Bcl-2 inhibitor enabled PDT and reversed apoptotic resistance, demonstrating a potent inhibitory effect on tumor growth.

Funder

National Natural Science Foundation of China

Key Technologies Research and Development Program of Guangzhou

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D4BM00083H

Reference34 articles.

1. Cancer Immunotherapy

2. T-cell therapy at the threshold

3. Immunology beats cancer: a blueprint for successful translation

4. The hallmarks of successful anticancer immunotherapy

5. Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

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