A machine learning-integrated stepwise method to discover novel anti-obesity phytochemicals that antagonize the glucocorticoid receptor-Reference-Cited by-同舟云学术

A machine learning-integrated stepwise method to discover novel anti-obesity phytochemicals that antagonize the glucocorticoid receptor

Author:

Shin Seo Hyun¹^ORCID,Hur Gihyun¹,Kim Na Ra¹,Park Jung Han Yoon²^ORCID,Lee Ki Won¹²³^ORCID,Yang Hee⁴^ORCID

Affiliation:

1. Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea

2. Bio-MAX Institute, Seoul National University, Seoul, 08826, Republic of Korea

3. Advanced Institutes of Convergence Technology, Seoul National University, Suwon, 16229, Republic of Korea

4. Department of Food and Nutrition, Kookmin University, Seoul 02707, Republic of Korea

Abstract

This study developed and validated a machine learning-integrated stepwise method to discover novel anti-obesity phytochemicals through GR antagonism.

Funder

Ministry of Agriculture, Food and Rural Affairs

Seoul National University

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

Reference82 articles.

1. Obesity, https://www.who.int/health-topics/obesity#tab=tab_1 (accessed September 14, 2021)

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