Gut indigenous Ruminococcus gnavus alleviates constipation and stress-related behaviors in mice with loperamide-induced constipation

Author:

Li Rong1,Xu Sheng2,Li Bei1,Zhang Bo3,Chen Weihua4,Dai Die4,Liu Zhi1ORCID

Affiliation:

1. Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular Imaging, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu Road, Hongshan District, Wuhan 430074, Hubei, China

2. School of Bioengineering, Wuhan Polytechnic, Wuhan, China

3. Xi'an Mayinglong Anorectal Hospital, Xi'an, China

4. Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-Imaging, Center for Artificial Biology, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China

Abstract

Refractory constipation is the most severe form of constipation, and its etiology remains unknown.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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