The foreign body response: emerging cell types and considerations for targeted therapeutics

Author:

Yang Brenda1,Rutkowski Natalie1,Elisseeff Jennifer12ORCID

Affiliation:

1. Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA

2. Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Abstract

The emerging role of T cells, stromal cells, and senescent cells and their interactions with other cell types in the FBR are discussed in this review. Additionally, factors that modulate the phenotype of these cells are briefly considered.

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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