A novel, rapid, and sensitive homogeneous sandwich detection method of Glypican-3 as a serum marker for hepatocellular carcinoma-Reference-Cited by-全球学者库

A novel, rapid, and sensitive homogeneous sandwich detection method of Glypican-3 as a serum marker for hepatocellular carcinoma

Published:2017 Issue:90 Volume:53 Page:12209-12212
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Han Naihan¹²³⁴⁵,Wang Wenshuang¹²³⁴⁵,Lu Danrong¹²³⁴⁵,Wang Han¹²³⁴⁵,Ma Xinying⁶⁷⁸⁵,Fan Xiaopeng⁹¹⁰³⁴⁵,Li Fuchuan¹²³⁴⁵^ORCID

Affiliation:

1. National Glycoengineering Research Center

2. and Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology

3. Shandong University

4. Jinan 250100

5. P. R. China

6. Department of Chemistry and Chemical Engineering

7. Heze University

8. Heze 274015

9. Department of Hepatology

10. Qilu Hospital

Abstract

Based on multiple interactions and fluorescence quenching, we report a novel homogeneous detection method for Glypican-3 which shows a series of significant advantages, and has great potential in the clinical diagnosis of hepatocellular carcinoma and proteoglycan detection.

Funder

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/CC/C7CC06305A

Reference43 articles.

1. PROTEOGLYCANS: STRUCTURES AND INTERACTIONS

2. Proteoglycans in prostate cancer

3. Glypicans: proteoglycans with a surprise

4. Glypican-3 as a potential differential diagnosis marker for hepatocellular carcinoma: A tissue microarray-based study

5. Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila

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