Synthesis of quinoxalines and assessment of their inhibitory effects against human non-small-cell lung cancer cells-Reference-Cited by-同舟云学术

Synthesis of quinoxalines and assessment of their inhibitory effects against human non-small-cell lung cancer cells

Published:2024 Issue:39 Volume:14 Page:28659-28668
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Liang Jia-Hua¹,Cho Shu-Tse²,Shih Tzenge-Lien²,Chen Jih-Jung¹³⁴⁵^ORCID

Affiliation:

1. Institute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan

2. Department of Chemistry, Tamkang University, 251301 Tamsui Dist., New Taipei City, Taiwan

3. Department of Pharmacy, School of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan

4. Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 404333, Taiwan

5. Traditional Herbal Medicine Research Center, Taipei Medical University Hospital, Taipei 110301, Taiwan

Abstract

Twenty-six quinoxalin derivatives were synthesized to assess their biological activities against human non-small-cell lung cancer cells (A549 cells). Among them, compound 4m exhibited the most potent inhibitory activity against A549 cells.

Funder

National Science and Technology Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA04453C

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