Antitumor effects of a Sb-rich polyoxometalate on non-small-cell lung cancer by inducing ferroptosis and apoptosis-Reference-Cited by-同舟云学术

Antitumor effects of a Sb-rich polyoxometalate on non-small-cell lung cancer by inducing ferroptosis and apoptosis

Published:2024 Issue: Volume: Page:
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Lin Jie-Wei¹,Zhou Yang²³,Xiao Hui-Ping²,Wu Lei-Lei⁴^ORCID,Li Peng-Cheng⁵,Huang Ming-Dong²³,Xie Dong¹,Xu Peng³,Li Xin-Xiong²^ORCID,Li Zhi-Xin¹

Affiliation:

1. Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China

2. College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China

3. College of Biological Science and Engineering, Fuzhou University, Fuzhou, Fujian 350108, China

4. Department of Thoracic Surgery, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310005, China

5. Shanghai Tumor Hospital, Fudan University, Shanghai 200032, China

Abstract

This study first reveals the ferroptosis antitumor mechanism of a Sb-rich polyoxometalate (POM) for non-small cell lung cancer therapy and demonstrates ferroptosis and apoptosis as a highly potent antitumor strategy for POM-based antitumor therapy.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D4SC03856H

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