Silver(<scp>i</scp>) complexes containing antifungal azoles: significant improvement of the anti-<i>Candida</i> potential of the azole drug after its coordination to the silver(<scp>i</scp>) ion-Reference-Cited by-同舟云学术

Silver(i) complexes containing antifungal azoles: significant improvement of the anti-Candida potential of the azole drug after its coordination to the silver(i) ion

Published:2024 Issue:5 Volume:53 Page:2218-2230
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Stanković Mia¹^ORCID,Kljun Jakob²^ORCID,Stevanović Nevena Lj.¹^ORCID,Lazic Jelena³^ORCID,Skaro Bogojevic Sanja³^ORCID,Vojnovic Sandra³^ORCID,Zlatar Matija⁴^ORCID,Nikodinovic-Runic Jasmina³^ORCID,Turel Iztok²^ORCID,Djuran Miloš I.⁵^ORCID,Glišić Biljana Đ.¹^ORCID

Affiliation:

1. University of Kragujevac, Faculty of Science, Department of Chemistry, R. Domanovića 12, 34000 Kragujevac, Serbia

2. University of Ljubljana, Faculty of Chemistry and Chemical Technology, Večna pot 113, SI-1000, Ljubljana, Slovenia

3. University of Belgrade, Institute of Molecular Genetics and Genetic Engineering, Vojvode Stepe 444a, 11042 Belgrade, Serbia

4. University of Belgrade-Institute of Chemistry, Technology and Metallurgy, Department of Chemistry, Njegoševa 12, 11000 Belgrade, Serbia

5. Serbian Academy of Sciences and Arts, Knez Mihailova 35, 11000 Belgrade, Serbia

Abstract

The clinically used antifungal agents, econazole, voriconazole and clotrimazole, were successfully applied in the synthesis of novel silver(i)-azole complexes with significantly improved anti-Candida activity in respect to the parent organic drugs.

Funder

University of Ljubljana

Serbian Academy of Sciences and Arts

European Cooperation in Science and Technology

Science Fund of the Republic of Serbia

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja

Javna Agencija za Raziskovalno Dejavnost RS

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/DT/D3DT03010E

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1. Hidden Killers: Human Fungal Infections

2. A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise

3. Recent developments of metal-based compounds against fungal pathogens

4. Potential of agricultural fungicides for antifungal drug discovery